Publicações 2024
A Mediterranean diet improves glycation markers in healthy people and in those with chronic diseases: a systematic review of clinical trials.
Júlia Silva e Oliveira, Jéssica Aparecida da Silva, Brenda Vieira Machado de Freitas, Rita de Cassia Gonçalves Alfenas, Josefina Bressan
Nutrition Reviews, v.2024, p.1-15
Fator de impacto: 6.0
DOI: 10.1093/nutrit/nuae045
Resumo: Context: Consumption of the Mediterranean diet (MedDiet) has beneficial effects on cardiometabolic health and aging. Objective: This systematic review aimed to critically investigate the effect of the MedDiet on glycation markers in healthy or overweight individuals with type 2 diabetes or cardiovascular disease. Data Sources: MEDLINE, EMBASE, Web of Science, and the Cochrane Library were
searched, using the terms “Mediterranean diet” AND “glycation end products, advanced”. Data Extraction: Three randomized and 3 nonrandomized clinical trials, containing data on 2935 adult and elderly individuals with normal weight or overweight, were included. All extracted data were compiled, compared, and critically analyzed. Data Analysis: The authors of most of the studies demonstrated a reduction in serum concentrations of advanced glycation end products (AGEs), such as eN-carboxymethyllysine and methylglyoxal, and in skin autofluorescence levels after at least 4 weeks of adherence to the MedDiet. The MedDiet also led to positive effects on gene expression of receptors for AGEs, as RAGE and AGER1, and
an enzyme involved in detoxification (glyoxalase I). There is no evidence that short-term adherence affects glycation markers. Conclusions: Glycation markers improved in response to the MedDiet. The possible mechanisms involved may be related to the low AGE and refined sugars content of the diet, as well as its high monounsaturated fatty acid, phenolic compound, and dietary fiber contents.
Systematic Review Registration: PROSPERO registration no. CRD42021284006.
Adequação do Consumo de Ácidos Graxos entre Pacientes em Prevenção Cardiovascular Secundária.
Aline Marcadenti, Rachel H. Vieira Machado, Sônia Lopes Pinto, Josefina Bressan, Bernardete Weber, Ângela Cristine Bersch-Ferreira
Arquivos Brasileiros de Cardiologia, v.121, p.1-11.
Fator de impacto: 2.6
DOI: 10.36660/abc.20230487.
Resumo: Fundamento: A adesão à uma alimentação adequada em macronutrientes é fundamental para a prevenção secundária de doenças cardiovasculares. Objetivo: Avaliar a prevalência de adesão às recomendações de consumo de ácidos graxos para prevenção e tratamento de doenças cardiovasculares, e estimar se a presença de determinados fatores de risco cardiovascular estaria associada à adesão.
Métodos: Estudo transversal com os dados de linha de base de 2358 participantes do estudo “Brazilian Cardioprotective Nutritional Program Trial”. Dados de consumo alimentar, e fatores de risco cardiovascular foram avaliados. Foi considerada, de acordo com a Sociedade Brasileira de Cardiologia, uma ingestão adequada de ácidos graxos poliinsaturados (AGPI) ≥10% do consumo total de energia diária, para ácidos graxos monoinsaturados (AGM), 20% e para ácidos graxos saturados (AGS), <7%. Na análise estatística foi considerando nível de significância de 5%. Resultados: Nenhum participante aderiu a todas as recomendações de forma simultânea e mais da metade (1482 [62,9%]) não aderiu a nenhuma recomendação. A adesão exclusivamente à recomendação de AGS foi a mais prevalente, sendo cumprida por 659 (28%) dos participantes, seguida da adesão exclusivamente à recomendação de AGP (178
[7,6%]) e de AGM (5 [0,2%]). Não houve associação entre o número de comorbidades e a adesão às recomendações nutricionais (p =0,269). Os participantes da região Nordeste do país apresentaram maior proporção de adesão às recomendações para consumo de AGS (38,42%), e menor para ingestão de AGPI (3,52%) (p <0,001) em comparação às demais. Conclusões: Na amostra avaliada, evidenciou-se baixa adesão às recomendações nutricionais para consumo de ácidos graxos.
Are ambulatory blood pressure parameters associated more with central adiposity than with total adiposity? Results of the ELSA-Brasil study.
Ângela Maria Natal de Souza, Rosane Harter Griep, Helen Hermana Miranda Hermsdorff, Maria de Jesus Mendes da Fonseca, Leidjaira Juvanhol Lopes
Frontiers in Cardiovascular Medicine, v. 10 p.1-10.
Fator de impacto: 3.6
DOI: 10.3389/fcvm.2023.1286726
Resumo: Background: Worldwide obesity has a high prevalence, as well as carries a high risk of several chronic diseases, including hypertension. Studies of the association between obesity and ambulatory blood pressure (BP) are scarce and most use only body mass index (BMI) as indicator of adiposity. Thus, we aimed to examine for associations between total and central adiposity and ambulatory BP parameters (BP means and variability, nocturnal dipping and morning surge) among participants in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Methods: This cross-sectional study (2012–2014) used a subsample of participants (n = 812) of ELSA-Brasil who underwent 24-hour ambulatory BP monitoring to assess systolic and diastolic BP (SBP and DBP, respectively) over 24-hour periods and sub-periods. Indicators for total adiposity were BMI and body fat (BF) and, for central adiposity, waist circumference (WC) and waist-to-height ratio (WHR). Associations were tested using crude and adjusted gamma and logistic regression. Results: Overweight (BMI) and abdominal obesity (WC and WHR) associated positively with mean 24-hour (Coef = 2.71, 3.09 and 4.00, respectively), waking (Coef = 2.87, 3.26 and 4.16, respectively), and sleeping (Coef = 2.30, 2.74 and 3.50, respectively) SBP; mean DBP associated with high WHR in these three periods (Coef = 2.00, 2.10 and 1.68, respectively) and with WC in the waking period (Coef = 1.44). Overweight and abdominal obesity (WC and WHR) were positively associated with SBP variability over 24 h (Coef = 0.53, 0.45 and 0.49, respectively) and in sleep (Coef = 0.80, 0.74 and 0.59, respectively), and with DBP variability in 24 h (Coef = 0.64, 0.73 and 0.58, respectively), wakefulness (Coef = 0.50, 0.52 and 0.52, respectively) and sleep (Coef = 0.53, 0.45 and 0.49); excess BF associated positively with DBP variability over 24 h (Coef = 0.43) and in wakefulness (Coef = 0.38). Lastly, high WHR and excess BF were associated with higher odds of extreme dipping (OR = 1.03 for both), while high WC and WHR associated with higher odds of exacerbated diastolic morning surge (OR = 3.18 and 3.66, respectively). Conclusion: Indicators of adiposity were associated with the BP means and variability, nocturnal dipping and morning surge, with more substantial results for indicators of central adiposity that the others.
Baixa ingestão de proteínas está associada à mortalidade em idosos brasileiros
Ângela Maria Natal de Souza, Dalila Pinto de Souza Fernandes, Isah Rabiu, Jérsica Martins Bittencourt, Juliana Farias de Novaes, Andréia Queiroz Ribeiro
Revista Brasileira de Geriatria e Gerontologia, v.27, p. 1-10,
DOI: 10.1590/1981-22562024027.230206
Resumo: Objetivo. Estimar a associação entre baixa ingestão de proteínas e mortalidade em pessoas idosas. Métodos. Estudo prospectivo realizado com 621 pessoas idosas da cidade de Viçosa (Minas Gerais), município de médio porte no Brasil. A ingestão de proteínas foi avaliada na linha de base (2009) pelo recordatório de ingestão habitual e foi utilizada a classificação de ingestão de proteínas proposta pela Sociedade Brasileira de Nutrição Parenteral e Enteral. Os dados de mortalidade foram coletados no período de acompanhamento (2009 a 2018) através do Sistema de Informações sobre Mortalidade. Modelos de regressão de Cox foram aplicados para estimar a associação independente entre ingestão total de proteínas e mortalidade, e estimativas de hazard ratio e seus respectivos intervalos de confiança de 95% foram calculados. Resultados. Entre os 621 participantes do estudo, 52,7% eram do sexo feminino e a prevalência de baixa ingestão proteica foi de 60,9%. Ao longo dos 9 anos de acompanhamento ocorreram 154 óbitos (23,3%). No modelo ajustado, pessoas idosas com baixa ingestão de proteínas apresentaram maior risco de morte [HR: 1,72; IC 95%: 1,05 – 2.82]. Conclusão. A baixa ingestão de proteínas pode aumentar o risco de morte em pessoas idosas.
Cashew nut (Anacardium occidentale L.) and cashew nut oil reduce cardiovascular risk factor in adults on weight-loss treatment: a randomized controlled three-arm trial (Brazilian Nuts Study).
Talitha Silva Meneguelli, Ana Claudia Pelissari Kravchychyn, Aline Lage Wendling, Ana Paula Dionísio, Josefina Bressan, Hercia Stampini Duarte Martino, Elad Tako, Helen Hermana Miranda Hermsdorff
Frontiers in Nutrition. V.11, p.1-12,
Fator de imapcto: 5.0
DOI: 10.3389/fnut.2024.1407028
Resumo: Introduction: Cashew nut contains bioactive compounds that modulate satiety and food intake, but its effects on body fat during energy restriction remains unknown. This study aimed to assess the effects of cashew nut and cashew nut oil on body fat (primary outcome) as well as adiposity, cardiometabolic and liver function markers (secondary outcomes). Materials and Methods: An eight-week (8-wk) randomized controlled-feeding study involved 68 adults with overweight/obesity (40 women, BMI: 33 ± 4 kg/m 2 ). Participants were randomly assigned to one of the energy-restricted (-500 kcal/d) groups: control (CT, free-nuts), cashew nut (CN, 30 g/d), or cashew nut oil (OL, 30 mL/d). Body weight, body composition, and blood collection were assessed at the baseline and endpoint of the study.
Chemical composition, processing, and health-promoting potential of unconventional food plants.
Maria Anete Santana Valente, Daniela da Silva Oliveira, Ângela Giovana Batista, Ceres Mattos Della Lucia, Leandro de Morais Cardoso
Frontiers in Nutrition, v. 2024, p.1-2.
Fator de impacto: 5.0
DOI: 10.3389/fnut.2024.1368629
Resumo: The 2030 Agenda for Sustainable Development has among its goals the eradication of poverty, the end of hunger, and malnutrition. Certainly, the achievement of this objective involves diversifying the diet and encouraging the identification and consumption of accessible, nutritious, and bioactive compound-rich alternative food sources. Currently, there is a very limited number of plant species used in human nutrition. There are still many unconventional food plants (UFP) unknown or underutilized by the general population due to their low popularity, lack of use, biodiversity loss, and traditional knowledge decline. Unconventional edible plants include fruits, leaves, roots, seeds, stems, and/or flowers of non-domesticated species that grow spontaneously in nature. Many of these plants have been widely incorporated into human diets as a result of increasing research into new sustainable food sources with high nutritional value, in addition to bioactive compounds. The use of UFP in diet can promote cultural diversification, especially in family farming, as they are part of the dietary tradition of many
Consumption of foods with a higher degree of processing is associated with overweight and abdominal obesity in women with breast cancer undergoing chemotherapy.
Elaine Estevam, Leidjaira Juvanhol Lopes, Sarah Aparecida Vieira Ribeiro, Maria Sônia Lopes Duarte, Solange Silveira Pereira, Eliana Carla Gomes de Souza
International Journal of Food Sciences and Nutrition, v. 2024, p.1-10.
Fator de imapcto: 3.9
DOI: 10.1080/09637486.2024.2316731
Resumo: This study evaluated food consumption according to its degree of processing and its relationship with body adiposity in 218 women with breast cancer. Food consumption was categorised according to the NOVA classification. Two groups were formed, the first composed by consumption of in natura, minimally processed foods and culinary ingredients (less processed foods) and the second one of processed and ultra-processed foods (more processed foods). The increase of 5% in the caloric contribution of more processed foods was associated with a 4% increase in the prevalence of overweight (p = 0.028) and 3% in prevalence of abdominal obesity (p = 0.018). This reinforces the importance of evaluating food consumption with a focus on the degree of processing, as it can contribute to the prevention of excess body fat in this group, as this excess is associated with a worse prognosis and survival.
Contribution of Ultra‑Processed Foods to Weight Gain Recurrence 5 Years After Metabolic and Bariatric Surgery.
Stephany L. Lobão, Adler S. Oliveira, Josefna Bressan, Sônia Lopes Pinto
Obesity Surgery, v.2024, p.1-7.
Fator de imapcto: 2.9
DOI: 10.1007/s11695-024-07291-5
Resumo: Background. The aim of this study was to evaluate evolution of ultra-processed food intake and recurrent weight gain in patients who underwent Roux-en-Y gastric bypass.
Materials and Methods. This study is an observational longitudinal study that evaluated patients who underwent metabolic and bariatric surgery at four time points: before surgery and at 3, 12, and 60 months after surgery. Anthropometric and dietary intake data were collected through two 24-h dietary recalls. All foods consumed were classified according to degree of processing. Recurrent weight gain was considered the difference between current weight and nadir weight. Results. The sample consisted of 58 patients with a mean age of 38.7 ± 8.9 years and 68% female. After 60 months, mean excess weight loss and recurrent weight gain were 73.6 ± 27.2% and 22.5 ± 17.4%. Calorie and macronutrient intake decreased significantly between the pre-surgery period, and 3 and 12 months post-surgery; however, there was no significant difference after 60 months. In relation to food groups or macronutrients, no difference was observed between the pre-surgery period and 60 months post-surgery. The contribution of unprocessed or minimally processed foods to calorie intake gradually decreased after 3 months post-surgery. Conclusion. The profile of dietary intake after 60 months of metabolic and bariatric surgery tends to approach that of the pre-surgery period. The contribution of unprocessed and minimally processed foods to calorie intake decreased after 60 months, while ultra-processed food contribution increased.
Conventional and germinated pearl millet flour (Pennisetum glaucum (L.) R. Br.) improves iron metabolism and antioxidant capacity in Wistar rats.
Jaqueline Maciel Vieira Theodoro, Bárbara Pereira da Silva, Renata Celi Lopes Toledo, Mariana Grancieri, Pietra Vidal Cardoso do Prado, Izabela Maria Montezano de Carvalho, Carlos Wanderlei Piler Carvalho, Hércia Stampini Duarte Martino
Journal of Cereal Science, v.116, p. 1-10.
Fator de imapcto: 3.8
DOI: 10.1016/j.jcs.2023.103840
Resumo: The study evaluated the effect of the consumption of pearl millet whole grain pre-cooked conventional, germinated and extruded flours on iron metabolism and antioxidant capacity in rats. The animals received iron-free standard diet (SD iron-free) for 28 days and subsequently, were separated into 4 groups: ferrous sulfate (SD + FS), conventional millet flour (SD + CM), germinated millet flour (SD + GM), and extruded millet flour (SD + EM), for 21 days. The SD iron free group presented increased ferroportin, hephaestin and ferritin gene expression and MDA concentration compared to the SD + FS group. The SD + GM group increased DcytB, ferroportin and hephaestin gene expression. The SD + EM group increased the concentration of transferrin compared to the SD + FS group and serum iron, compared to the other groups, while reducing the liver’s total antioxidant capacity (TAC). The SD + CM group increased ferritin expression. All test groups increased the gene expression of DMT1 and hephaestin, as well as serum iron and reduced transferrin, Nrf2 and TNF gene expression, and MDA, NO, SOD and CAT levels in relation to the SD + FS group. In view of this, millet provides promising bioavailability of iron. Besides, germination stands out for improving iron metabolism in relation to extrusion and is similar to conventional millet in antioxidant capacity.
Daily Cashew and Brazil Nut Consumption Modifies Intestinal Health in Overweight Women on Energy-Restricted Intervention: A Randomized Controlled Trial (Brazilian Nuts Study).
Brenda Kelly Souza Silveira, Daniela Mayumi Usuda Prado Rocha, Hércia Stampini Duarte Martino, Mariana Grancieri, Mariana Juste Contin Gomes, Hilário Cuquetto Mantovani, Josefina Bressan, Helen Hermana Miranda Hermsdorff
The Journal of Nutrition, v.154, p. 962-977.
Fator de imapcto: 4.2
DOI: 10.1016/j.tjnut.2023.12.022
Resumo: Background. Increased intestinal permeability and dysbiosis are related to obesity. Nuts can provide nutrients and bioactive compounds that modulate gut microbiota and inflammation, enhancing the beneficial effects of weight loss. Objectives. To evaluate the effect of consuming cashew nuts (Anacardium occidentale L.) and Brazil nuts (Bertholletia excelsa H.B.K) on intestinal permeability and microbiota, fecal SCFAs and pH, inflammation, and weight loss in energy restriction condition. Methods. In this 8-week randomized controlled trial, 40 women with overweight or obesity were assigned to energy-restricted groups (−500 kcal/d): control group (free of nuts) or Brazilian nuts group (BN: 30 g of cashew nuts and 15 g of Brazil nuts per day). Permeability was analyzed by the lactulose/mannitol test and the microbiota by sequencing the 16S gene in the V3-V4 regions. Plasma concentrations of inflammatory cytokines (TNF, IL-6, IL-10, IL-8, IL-17A) and C-reactive protein were analyzed. Results. In total, 25 women completed the intervention. Both groups lost weight without statistical differences. Lactulose excretion increased only in the control group (P < 0.05). The BN consumption increased fecal propionic acid and potentially beneficial bacteria, such as Ruminococcus, Roseburia, strains NK4A214 and UCG-002 from the Ruminococcaceae family, but also Lachnospiraceae family, Bacteroides, and Lachnoclostridium, when compared to the control group. Changes in intestinal permeability were correlated to a greater reduction in body fat (kg), and IL-8, and increases in Ruminococcus abundance. Conclusion. Our findings demonstrate a positive impact of BN consumption within an energy-restricted context, linked to the augmentation of potentially beneficial bacteria and pathways associated with body fat reduction. Besides, BN consumption mitigated increased intestinal permeability, although its capacity to diminish permeability or enhance weight loss proved limited.
Dietary advanced glycation end products, body composition, and anthropometric measures: a cross-sectional analysis in women with excess body weight.
Nélia pinheiro Mendes, Flávia Galvão Cândido, Flávia Xavier Valente, Maria do Carmo Gouveia Peluzio, Leidjaira Juvanhol Lopes, Rita de Cassia Gonçalves Alfenas
NMCD. Nutrition Metabolism and Cardiovascular Diseases,v. 34, p. 1-10.
Fator de imapcto: 3.9
DOI: 10.1016/j.numecd.2024.03.011
Resumo: Background. Evidence suggests that changes in advanced glycation end‐products (AGEs) may influence body weight. Previous studies have focused on cooking methods as the primary way how to reduce the dietary AGEs but little is known about the effects of a change in diet composition. Objective. The aim of this study was to assess the effects of a low‐fat plant‐based diet on dietary AGEs and test the association with body weight, body composition, and insulin sensitivity. Methods. Participants who were overweight (n = 244) were randomly assigned to an intervention (low‐fat plant‐based) (n = 122) or control group (n = 122) for 16 weeks. Before and after the intervention period, body composition was measured by dual X‐ray absorptiometry. Insulin sensitivity was assessed with the predicted insulin sensitivity index (PREDIM). Three‐day diet records were analyzed using the Nutrition Data System for Research software and dietary AGEs were estimated, using a database. Repeated measure ANOVA was used for statistical analysis. Results. Dietary AGEs decreased in the intervention group by 8768 ku/day on average (95% −9611 to −7925; p < 0.001), compared with the control group (−1608; 95% CI −2709 to −506; p = 0.005; treatment effect −7161 ku/day [95% CI −8540 to −5781]; Gxt, p < 0.001). Body weight decreased by 6.4 kg in the intervention group, compared with 0.5 kg in the control group (treatment effect −5.9 kg [95% CI −6.8 to −5.0]; Gxt, p < 0.001), largely due to a reduction in fat mass, notably visceral fat. PREDIM increased in the intervention group (treatment effect +0.9 [95% CI + 0.5 to +1.2]; p < 0.001). Changes in dietary AGEs correlated with changes in body weight (r = +0.41; p < 0.001), fat mass (r = +0.38; p < 0.001), visceral fat (r = +0.23; p < 0.001), and PREDIM (r = −0.28; p < 0.001), and remained significant even after adjustment for changes in energy intake (r = +0.35; p < 0.001 for body weight; r = +0.34; p < 0.001 for fat mass; r = +0.15; p = 0.03 for visceral fat; and r = −0.24; p < 0.001 for PREDIM). Conclusions. Dietary AGEs decreased on a low‐fat plant‐based diet, and this decrease was associated with changes in body weight, body composition, and insulin sensitivity, independent of energy intake. These findings demonstrate positive effects of qualitative dietary changes on dietary AGEs and cardiometabolic outcomes.
Effect of combined physical exercise on inflammatory markers and the relationship with body composition in young women.
Lucimar Aguiar da Silva, Deyliane Aparecida de Almeida Pereira, Sarah Aparecida Vieira Ribeiro, Catarina Maria Nogueira de Oliveira Sediyama, Silvia Eloiza Priore
Journal of Bodywork and Movement Therapies, v.39, p.73-78.
Fator de impacto: 1.4
DOI: 10.1016/j.jbmt.2024.02.046
Resumo: Objectives. To evaluate the effect of eight weeks of combined physical exercise of moderate intensity on inflammatory markers, as well as its relationship with body composition in young women recently admitted to a Public Institution of Higher Education. Methods. Longitudinal, intervention study, in which 59 female participants aged 18–25 years were evaluated before and after a combined physical exercise program for eight weeks. Blood samples were collected before and after the intervention for analysis of C-reactive protein and inflammatory cytokines. Weight and height were measured to calculate body mass index and body composition was evaluated by Dual Energy X-Ray Absorptiometry before and after the intervention. Statistical analyzes performed were t-test, Willcoxon test and Spearman’s correlation. This study was approved by the Human Research Ethics Committee and the Free and Informed Consent Form was signed by all participants. Results. After the intervention, there was a reduction in the pro-inflammatory cytokines (IL-1β, IL-6, TNF and IL-12), while the anti-inflammatory (IL-10) and CRP did not change; reduction in the total body gynoid fat mass and in the percentage of body fat; increased trunk and total muscle mass. Body composition was negatively correlated with the pro-inflammatory interleukins IL-1β and IL-6 and positively correlated with CRP. Conclusions. Combined physical exercise for eight weeks acted to reduce pro-inflammatory cytokines, fat mass and increase in muscle mass. Inflammatory markers correlated with body fat before the intervention, suggesting the participation of visceral adipose tissue in the release of these markers in female university students.
Fatty acid intake and prevalence of depression among Brazilian graduates and postgraduates (CUME Study).
Thaís da Silva Sabião, Fátima Costa de Oliveira, Josefina Bressan, Adriano Marçal Pimenta, Helen Hermana Miranda Hermsdorff, Fernando Luiz Pereira de Oliveira, Raquel de Deus Mendonça, Júlia Cristina Cardoso Carraro
Journal of Affective Disorders, v. 346, p. 182-191.
Fator de imapcto: 6.6
DOI: 10.1016/j.jad.2023.11.012
Resumo: Background. Dietary fatty acids are related to the development of several inflammatory-related diseases, which may include depression. So, the association between fatty acids, culinary oils and fat intake and depression in highly educated Brazilians was evaluated. Methods. Multicenter cross-sectional study using baseline data from the Cohort of Universities of Minas Gerais. The diagnosis of depression was self-reported, and the daily intake of fatty acids was assessed using a 144-item food frequency questionnaire (FFQ). Results. A total of 7157 participants (68.83 % women) with a median age of 33 years were included. The prevalence of depression was 12.60 % (N = 902). In the adjusted analyses, it was observed that individuals with the highest intake of omega-6 fatty acids (n-6) (OR: 1.36, 95 % CI 1.11–1.67) had a higher prevalence of depression. This increased n-6 intake was identified as a risk factor for depression only among male participants, while among overweight participants, higher n-6 intake was also positively associated with depression. Conversely, a higher ratio of polyunsaturated to monounsaturated and saturated fatty acids (PM/S) was also found to be positively associated with depression, but this association was observed only among non-overweight participants. No associations were found between the consumption of culinary oils or fats and depression. Limitations. Cross-sectional design limits the assessment of causality. The use of the FFQ can make estimates more difficult. Conclusion. Higher consumption of n-6, and higher PM/S ratios were associated with depression, and individual factors can interfere. The mental health care policies should include specific nutritional strategies.
Green banana biomass anti-obesogenic, anti-hyperlipidemic, antidiabetic, and intestinal function potential effects: a systematic review.
Natália da Silva Bomfim, Renata de Souza Ferreira, Julia Silva e Oliveira, Rita de Cássia Gonçalves Alfenas
Nutrition Reviews, v.2024, p.1-14.
Fator de impacto: 6.1
DOI: 10.1093/nutrit/nuae040
Resumo: Context. Apparently, the consumption of resistant-starch food sources, such as green banana biomass, stimulates the proliferation of short-chain fatty acid intestinal bacteria producers, which can contribute to intestinal health and reduce the risk of chronic diseases. However, the available scientific evidence is scarce and no study has systematically evaluated such evidence. Objective. The aim of this study was to analyze the potential effects of green banana biomass on anthropometry, body composition, and biochemical and intestinal variables in humans and animals. Data Sources. The Cochrane Library, Embase, Medline/PubMed, Scopus, and Web of Science electronic databases were searched in January 2024 for eligible articles. Studies that tested the effects of cooked peeled or unpeeled green banana on anthropometric, biochemical, and/or intestinal variables were included. Data Extraction. This systematic review was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The classification and assessment of the quality of studies were based on the relevant criteria related to the design of these studies and the quality criteria checklist of the Academy of Nutrition and Dietetics manual. Twelve studies published between 2001 and 2021 were included in the review. Data Analysis. The results of human studies indicate that the ingestion of green banana biomass controlled intestinal dysfunction (50–300 g/day for 5–14 days or 30 g/day for 8 wk) in children, and showed potential anti-obesogenic, anti-hyperlipidemic, and antidiabetic (40 g/day for 24 wk) effects in adults. In rats, biomass consumption led to potential anti-obesogenic (25 g/day for 8 wk), anti-hyperlipidemic, and antidiabetic (∼8–30 g/day for 12 wk) effects. Conclusion. Consumption of green banana biomass seems to exert beneficial effects on intestinal function and potential effects on obesity, dyslipidemia, and diabetes. These effects may be related to increased fecal short-chain fatty acid concentrations as a result of type 3 resistant starch present in biomass.
Higher consumption of ultra-processed foods and a pro-inflammatory diet are associated with the normal-weight obesity phenotype in Brazilian children.
Bruna Clemente Cota, Mariana de Santis Filgueiras, Patrícia Feliciano Pereira, Leidjaira Lopes Juvanhol, Juliana Farias de Novaes
Nutrition, v.117, p. 1-7.
Fator de impacto: 4.4
DOI: 10.1016/j.nut.2023.112234
Resumo: Objectives. The aim of this study was to evaluate the relationship of ultra-processed food (UPF) consumption and the Children’s Dietary Inflammatory Index (C-DII) with the normal-weight obesity (NWO) phenotype in school-aged children. Methods. This cross-sectional study was carried out with a representative sample of 364 children ages 8 to 9 y in Viçosa, Minas Gerais, Brazil. The NWO phenotype was defined as normal weight according to body mass index and high body fat, assessed by dual-energy x-ray absorptiometry. Three 24-h dietary recalls were performed to evaluate NOVA classification groups and to calculate the C-DII score. Results. Among normal-weight children (NWO and “no NWO”), higher consumption of UPF (second tercile [T2]: prevalence ratio [PR], 1.9; 95% confidence interval [CI], 1.1–3.4; T3: PR, 1.8; 95% CI, 1.01–3.1) and a diet consisting of high proinflammatory foods (T2: PR, 1.7; 95% CI, 1.04,2.8) were associated with a higher prevalence of NWO, in relation to the first tercile. Similarly, among children with excess body fat independent of body mass index (NWO and excess of weight), higher consumption of UPF was associated with a higher prevalence of NWO (T2: PR, 2; 95% CI, 1.2–3.3) in relation to T1. Conclusion. Higher UPF consumption and a diet consisting of high proinflammatory foods were associated with the NWO phenotype in children.
Nutritional content, amino acid profile, and protein properties of edible insects (Tenebrio molitor and Gryllus assimilis) powders at different stages of development.
Lívya Alves Oliveira, Stephanie Michelin Santana Pereira, Kelly Aparecida Dias, Stefany da Silva Paes, Mariana Grancieri, Luis Gonzalo Salinas Jimenez, Carlos Wanderlei Piler de Carvalho, Eugenio Eduardo de Oliveira, Hércia Stampini Duarte Martino, Ceres Mattos Della Lucia
Journal of Food Composition and Analysis, v.125, p. 1-14.
Fator de impacto: 4.3
DOI: 10.1016/j.jfca.2023.105804
Resumo: Insects have great potential as ingredients for industrial purposes, providing good technological properties. This study aimed to characterize powders of Tenebrio molitor and Gryllus assimilis at two developmental stages for potential use in human nutrition. The insect powders were analyzed for their proximate composition, mineral content, carotenoids, vitamins C and E, riboflavin, niacin, amino acid profile, in vitro protein digestibility, solubility as a function of pH, foam-forming, and water and oil-holding capacity. Both powders were excellent sources of proteins (ranging from 57.36 % to 67.97 %), phosphorus (512.00–732 mg/100 g), copper (1.45–3.01 mg/100 g), iron (5.41–8.41 mg/100 g), zinc (11.62–25.57 mg/100 g), manganese (1.63–8.08 mg/100 g), good sources of magnesium (84.00–180.00 mg/100 g), and sources of potassium (624.00–820.00 mg/100 g), and niacin (1.88–3.21 mg/100 g). The proteins showed good digestibility (84.48–92.53 %) and increased solubility in alkaline pH (∼11). Lysine was identified as the limiting amino acid for both species analyzed (EAAS: 0.55–0.79). The development stage of the insects influenced their nutritional content, amino acid profile, and functional protein properties. The data obtained support the potential use of these insect powders on a large scale and contribute to selecting the development stage with the best nutritional composition.
Obesogenic neighborhood environment is associated with body fat and low-grade inflammation in Brazilian children: could the mother’s BMI be a mediating factor?
Mariana De Santis Filgueiras, Milene Cristine Pessoa, Josefina Bressan, Ariene Silva do Carmo, Aline Siqueira Fogal Vegi, Fernanda Martins de Albuquerque, Juliana Farias de Novaes
Public Health Nutrition, v. 27, p. 1-11.
Fator de impacto: 3.2
DOI: 10.1017/S1368980023002628
Resumo: Objective: To evaluate the direct and indirect associations of obesogenic and leptogenic neighborhood environments with body fat, and pro- and anti-inflammatory adipokines in Brazilian children. Design: Cross-sectional study. The body fat distribution was assessed using dual-energy X-ray absorptiometry (DXA). Concentrations of leptin and adiponectin were measured. Four hundred meters (0·25 miles) road network buffer was the neighborhood unit used to assess the environmental characteristics around households. Obesogenic and leptogenic environments were the latent variables obtained from the observed characteristics. The mother’s BMI, ultra-processed food consumption, and physical activity before and after school, were tested as mediating variables. A hybrid model of structural equations was used to test the direct and indirect associations of obesogenic and leptogenic environments with body fat, leptin and adiponectin concentrations. Setting: Urban area of Viçosa, Minas Gerais, Brazil. Participants: Children aged 8- and 9-years (n 367). Results: Obesogenic environment was directly associated with the mother’s BMI (β: 0·24, P = 0·02) and the child’s body fat (β: 0·19, P = 0·02). The mother’s BMI and body fat mediated the association of the obesogenic environment with leptin concentrations (β: 0·05, P = 0·02). Conclusions: Obesogenic neighborhood environment was directly associated with body fat and mother’s BMI, and indirectly associated with leptin concentrations in Brazilian children, mediated by the mother’s BMI and body fat.
Probiotic Flavored Fermented Goat Milk as an Adequate Vehicle for Beneficial Bacteria and Higher Total Phenolic and Antioxidant Activity.
Autores: Livia Bordalo Tonucci, Bárbara Pereira da Silva, Maria Eliza de Castro Moreira, Isabel Cristina Silva de Oliveira, Mariana Rodrigues Carneiro, Hércia Stampini Duarte Martino, Karina Maria Olbrich dos Santos
Austin Journal of Biotechnology & Bioengineering, v.11, p. 1129-1135.
DOI: www.austinpublishinggroup.com
Resumo: The study aimed to evaluate two grape flavored fermented goat milk produced with or without probiotics. Physicochemical characteristics, sensory analysis, antioxidant profile and probiotics viability of the dairy beverages were analyzed. The phenolic contents and antioxidant activity of probiotic milk were higher than conventional milk. A higher loss in cell viability was observed for L. acidophilus than for the B. animalis. The average sensory acceptability scores obtained by both dairy beverages were higher than 6.5. Therefore, the probiotic fermented milk showed an adequate vehicle for the probiotics with good viability, a higher total phenolic and antioxidant activity and good acceptability
Quality of life of older adults in Family Health Strategy: a cross-sectional study.
Laise Brilhante BatistaI, Annah Thereza Mota, Ana Luiza Blanco, Jéssica da Silva Marinho, Maria Sortênia Alves Guimarães, Andréia Queiroz Ribeiro, Daniella Pires Nunes
São Paulo Medical Journal, v. 142, p. 1-7.
DOI: 10.1590/1516-3180.2022.0445.R1.24042023
Resumo: BACKGROUND: With the increase in the older adult population, it is essential to identify the living and health conditions that can impact the quality of life of these individuals. OBJECTIVES: To identify the domains and factors associated with the quality of life of older adults under the Family Health Strategy program. DESIGN AND SETTING: This was a cross-sectional analytical study was conducted in the municipality of Palmas, Tocantins, Brazil. METHODS: We assessed 449 older adults enrolled in the Family Health Strategy program. Data were collected between April and July, 2018. World Health Organization Quality of Life Assessment (WHOQOL-OLD) was used to assess the quality of life (QoL) and multiple linear regression was used to estimate the factors associated with QoL. RESULTS: The QoL domain with the highest score was death and dying (mean = 70.4), and the lowest score was for sensory functions (mean = 61.0 points). The factors associated with QoL were single marital status (β = -4.55; P = 0.014), level of independence for daily living activities (β = 4.92; P < 0.001), self-assessment of regular health (β = 5.35; P < 0.001), and poor health (β = -8.67; P < 0.001). CONCLUSION: The death and dying domain of QoL presented the highest score. Marital status, impairment in daily activities, and health self-assessment were associated with QoL.
The Brazilian Cardioprotective Nutritional (BALANCE) Program improves diet quality in patients with established cardiovascular disease: Results from a multicenter randomized controlled trial.
Aline Rosignoli da Conceição, Alessandra da Silva, Leidjaira Lopes Juvanhol, Aline Marcadenti, Ângela Cristine Bersch-Ferreira, Bernardete Weber, Nitin Shivappa, Josefina Bressan
Nutrition Research, v. 121, p.82-94.
Fator de impacto: 4.5
DOI: doi.org/10.1016/j.nutres.2023.10.007
Resumo: Dietary modifications are essential strategies for cardiovascular disease prevention. However, studies are needed to investigate the diet quality of individuals undergoing secondary prevention in cardiology and who received dietary intervention based on cardiovascular disease management. We prospectively evaluated the diet quality in the Brazilian Cardioprotective Nutritional Program Trial (BALANCE Program Trial). We hypothesized that the BALANCE Program could improve patients’ dietary pattern according to different indices of diet quality such as the Dietary Inflammatory Index (DII); the dietary total antioxidant capacity; overall, healthful, and unhealthful Plant-Based Diet Index (PDI, hPDI, and uPDI, respectively); and modified Alternative Healthy Eating Index (mAHEI). This multicenter randomized, controlled trial included patients aged ≥45 years randomly assigned to either the experimental or control group. Data from 2185 participants at baseline and after 12, 24, 36, and 48 months showed that the intervention group (n = 1077) had lower mean values of DII and higher dietary total antioxidant capacity, PDI, hPDI, and mAHEI than the control group. The results also showed differences between the follow-up times for DII, hPDI, and uPDI (48 months vs baseline) and for PDI and mAHEI (24 months vs baseline), regardless of group. The interaction analysis demonstrated that the intervention group showed better results than the control group at 12, 24, 36, and 48 months for the DII and at months 12, 36, and 48 for the mAHEI. Our results provide prospective evidence that the BALANCE Program improved the diet quality in those in secondary cardiovascular prevention according to different indices, with the intervention group showing better results than the control group.
Ultra-processed food consumption and quality of life: a cross-sectional study in Iranian women.
Dorsa Hosseininasab, Farideh Shiraseb, Niki Bahrampour, Alessandra da Silva, Mohammad Mahdi Hajinasab, Josefina Bressan, Khadijeh Mirzaei
Frontiers in Public Health, v. 2024, p. 1-10.
Fator de impacto: 5.2
DOI: 10.3389/fpubh.2024.1351510
Resumo: Background: Ultra-processed foods (UPFs) have been associated with a higher intake of added sugars, sodium, and unhealthy fats; however, the relationship between UPFs and quality of life (QoL) is not well understood. Methods: The present cross-sectional study included 193 Iranian women aged 18–48 years with a body mass index (BMI) of ≥25 kg/m2. UPFs were identified using the NOVA classification. QoL was evaluated using the SF-36 questionnaire. Anthropometric measurements and body composition were assessed using an appropriate method. Results: The mean BMI and fat-free mass (FFM) of the subjects were 30.90 kg/m2 and 46.69 kg, respectively. At first, a significant difference was observed in the height of women across tertiles of UPF consumption. The mean score of the total QoL scale was 66.90. Women who were in the tertile 3 of UPFs intake had 23.59 units lower the scale of limitation in physical capabilities and activity (score of role-physical) (β = −23.59, 95% CI: −37.77–9.40, p = 0.001). Among those with the highest adherence to UPF intake, there was an 8.76 unit reduction in addressing feelings of energy and fatigue (vitality domain) in model 2 (β = −8.76, 95% CI: −16.42–1.11, p = 0.02). Finally, a reduction of 15.78 units was observed in the mental health scale, specifically in the mental states of anxiety and depression, among participants in the third tertile of UPF intake (β = −15.78, 95% CI: −24.11–7.45, p < 0.001). Conclusion: Increased UPF consumption was associated with lower QoL in Iranian women. Further studies are needed to confirm these findings and develop effective strategies to promote healthy food choices.
